Frappe Framework
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Frappe Framework is an open-source Python framework that includes a database layer, forms engine, and permission system out of the box. You define your data models in Frappe's DocType format, and the framework auto-generates a web interface with forms, lists, and reports. It's particularly well-suited for businesses that need a complete ERP or CRM system but want to avoid vendor lock-in.
Choose Frappe if you want control over your code and data while still moving quickly with database-driven features. Unlike SaaS platforms, you can self-host Frappe, modify the source code, and use it for complex multi-tenant applications, making it popular for consulting firms and enterprises with custom requirements.